Hydrocortisone skin creams come in different strengths that vary from 0.1% (1mg hydrocortisone in each gram of cream) to 2.5% (25mg hydrocortisone in each gram of cream). Where to get it - GP or pharmacy? You can only buy hydrocortisone cream up to a maximum 1% strength from a pharmacy. Cream from a pharmacy should only be used for: eczema.
Hydrocortisone Valerate Cream USP, 0.2% has produced mild, reversible adrenal suppression in adult patients when used under occlusion for 5 days, 15 grams twice a day over 25 to 60% body surface area or when used three times a day over 20 to 30% body surface area to treat psoriasis for 3-4 weeks. Patient characteristics for 72 patients with seborrheic dermatitis treated with ketoconazole 2% cream (n = 36) or hydrocortisone 1% cream (n = 36) Ketocunazole. (n = 36) Minimum Maximum Median Hydroeortisonet (n = 36) Minimum Maximum Median Age (yr) 18 78 34 18 73 32.0 Weight (kg) 50 102 67 48 100 67.5 Height (cm) 160 186 170 158 186. If you buy the 1% hydrocortisone cream over the counter and rub it in well, wait a half hour and reapply, you get about the same dosage as the 2.5% cream. The dosage is determined by the amount of rubbing and total amount of product applied. If you merely wipe on 2.5% cortisone you won't absorb as much cortisone as 1% cream thoroughly rubbed in. Hydrocortisone suppositories 100 mg Calculated to make 12 each (2-mL mold) Ingredients Hydrocortisone USP 1.200 g Silica gel (fumed silica USP/NF) 0.120 g Fatty acid blend 20.520 g Supplies Suppository molds, 2 mL Hot plate (with a stir bar option) Water bath; thermometer Beaker Stirring rod Ceramic or Wedgwood mortar and pestle Suggested Method 1.
Like other topical corticosteroids, hydrocortisone valerate has anti-inflammatory, antipruritic and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Pharmacokinetics -
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle and the integrity of the epidermal barrier. Occlusive dressings with hydrocortisone for up to 24 hours have not been demonstrated to increase penetration; however, occlusion of hydrocortisone for 96 hours markedly enhances penetration. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin may increase percutaneous absorption.
Studies performed with Hydrocortisone Valerate Cream USP, 0.2% indicate that it is in the medium range of potency as compared with other topical corticosteroids. Movist pro 2 2 150.
Hydrocortisone Cream 2.5 Percent
Class | Potency | Generic Name and Strength | Brand Name and Formulation |
Class I | Very Potent | Clobetasol Propionate 0.05% | Dermovate Cream / Ointment / Scalp Application |
Diflucortolone Valerate 0.3% | Nerisone Forte Oily Cream / Ointment | ||
Class II | Potent | Beclometasone Dipropionate 0.025% | Generic Beclometasone Dipropionate Cream / Ointment |
Betamethasone Valerate 0.1% | Betnovate Cream / Ointment / Lotion / Scalp Application | ||
Betamethasone Dipropionate 0.05% | Diprosone Cream / Ointment / Lotion | ||
Diflucortolone Valerate 0.1% | Nerisone Cream / Oily Cream / Ointment | ||
Fluocinolone Acetonide 0.025% | Synalar Cream / Ointment / Gel | ||
Fluocinonide 0.05% | Metosyn FAPG Cream / Ointment | ||
Fluticasone Propionate 0.05% | Cutivate Cream | ||
Fluticasone Propionate 0.005% | Cutivate Ointment | ||
Hydrocortisone Butyrate 0.1% | Locoid Cream / Ointment / Scalp Lotion Locoid Crelo Emulsion | ||
Mometasone Furoate 0.1% | Elocon Cream / Ointment / Scalp Lotion | ||
Triamcinolone Acetonide 0.1% | Aureocort Ointment * | ||
Class III | Moderate | Alclometasone Dipropionate 0.05% | Modrasone Cream |
Betamethasone Valerate 0.025% | Betnovate-RD Cream / Ointment | ||
Clobetasone Butyrate 0.05% | Eumovate Cream / Ointment | ||
Fludroxycortide 0.0125% | Haelan Cream / Ointment | ||
Fluocinolone Acetonide 0.00625% | Synalar 1 in 4 Dilution Cream / Ointment | ||
Fluocortolone 0.25% | Ultralanum Plain Cream / Ointment | ||
Class IV | Mild | Hydrocortisone 0.1-2.5% | Generic Hydrocortisone Cream / Ointment Dioderm Cream |
Fluocinolone Acetonide 0.0025% | Synalar 1 in 10 Dilution Cream |
* Compound preparation (also contains chlortetracycline hydrochloride 3%) Currencier 1 1 4 download free.
Notes
Drawoutx 2 0 1 Hydrocortisone Cream 2%
List of brand names and formulation is not exhaustive.
Hydrocortisone 2.5% Cream
Generic and brand name data from:
2.5% Hydrocortisone Cream Over The Counter
1. Joint Formulary Committee. BNF (British National Formulary) 69. 69th ed. London: British Medical Association and Royal Pharmaceutical Society of Great Britain; March 2015.
Hydrocortisone 2.5 Cream Uses
2. electronic Medicines Compendium – Summaries of Product Characteristics. Available at http://www.medicines.org.uk [Accessed on 29/07/15].